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Open Access Research

Rapid alterations of cell cycle control proteins in human T lymphocytes in microgravity

Cora S Thiel1,2, Katrin Paulsen1, Gesine Bradacs1,3, Karolin Lust3,4, Svantje Tauber1, Claudia Dumrese1,5, Andre Hilliger6, Kathrin Schoppmann1,3, Josefine Biskup1, Nadine Gölz1, Chen Sang7, Urs Ziegler5, Karl-Heinrich Grote3, Frauke Zipp8, Fengyuan Zhuang7, Frank Engelmann6,9, Ruth Hemmersbach10, Augusto Cogoli11 and Oliver Ullrich1,12,3*

Author Affiliations

1 Institute of Anatomy, Faculty of Medicine, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland

2 Institute of Medical Physics and Biophysics, University of Muenster, Heisenbergstrasse 11, 48149 Muenster, Germany

3 Department of Machine Design, Engineering Design and Product Development, Institute of Mechanical Engineering, Otto-von-Guericke-University Magdeburg, Universitaetsplatz 2, 39106 Magdeburg, Germany

4 Institute of Molecular and Clinical Immunology, Otto-von-Guericke-University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany

5 Center for Microsocopy and Image Analysis, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland

6 KEK GmbH, Kemberger Str. 5, 06905 Bad Schmiedeberg, Germany

7 School of Biological Science and Medical Engineering, Beihang University, 37 Xueyuan Rd., Beijing 100191, China

8 Clinic for Neurology, University Medical Center of Johannes Gutenberg-University Mainz, Langenbeckstraße 1, 55131 Mainz, Germany

9 University of Applied Science Jena, Carl-Zeiss-Promenade 2, 07745 Jena, Germany

10 German Aerospace Center (DLR), Institute of Aerospace Medicine, Linder Hoehe, 51147, Cologne, Germany

11 Zero-G Life Tec, Riedhofstrasse 273, 8049 Zurich, Switzerland

12 Zurich Center for Integrative Human Physiology (ZIHP), University of Zurich, Switzerland

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Cell Communication and Signaling 2012, 10:1 doi:10.1186/1478-811X-10-1

Published: 24 January 2012

Additional files

Additional file 1:

Short technical description of in-flight-hardware. A short summary of the most important technical parameters of the in-flight-hardware such as rack configuration, weight, dimensions and power supply.

Format: DOC Size: 27KB Download file

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Open Data