Figure 10.

Mpl from patients with AMM can be translated in vivo. Western blot analysis of lysates of 293 T cells transfected with pcDNA3/Mpl constructs from 15 AMM patients and 15 controls. Transfection lysates were analysed by 6% SDS PAGE. Blots were probed with Mpl antibody raised against the full length Protein. A representative blot with data for 5 controls and 5 patients is shown in this figure. The second band probably corresponds to non-glycosylated Mpl.