Table 1 |
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|
Eps15 binding partners |
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|
Binding partner |
Interacting domain |
Function |
Reference |
|
|
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|
α-adaptin |
DPF-motif |
Endocytosis |
[64] |
|
|
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|
γ-adaptin |
Domain III |
secretion |
|
|
|
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|
Crk |
PRMs |
Unknown |
[10] |
|
|
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|
Eps15/Eps15R |
EH domain |
Unknown |
[46] |
|
|
|||
|
Epsin |
EH domain |
Endocytosis/nucleus |
[51] |
|
|
|||
|
Grb2 |
PRMs |
Endocytosis |
|
|
|
|||
|
Hrb |
EH domain |
Nucleus/endocytosis |
|
|
|
|||
|
Hrs |
n.d. |
Sorting |
[74] |
|
|
|||
|
Intersectin |
Coiled-coil domain |
Endocytosis |
[41] |
|
|
|||
|
Numb |
EH domain |
Endocytosis |
[36] |
|
|
|||
|
Parkin |
UIM domains |
Mono-ubiquitination |
[17] |
|
|
|||
|
POB1 |
n.d. |
Endocytosis |
[79] |
|
|
|||
|
Phocein |
n.d. |
Trafficking |
[80] |
|
|
|||
|
Spartin |
n.d. |
Endocytosis |
[81] |
|
|
|||
|
STAM (EAST) |
n.d. |
Sorting |
[74] |
|
|
|||
|
Stonin2 |
EH domain |
Endocytosis |
[53] |
|
|
|||
|
Synaptojanin |
EH domain |
Endocytosis |
[82] |
|
|
|||
|
Ubiquilin/PLIC |
UIM1 |
Aggresome formation |
[49] |
|
|
|||
|
Ubiquitin |
UIM2 |
Ubiquitination/unknown |
|
|
|
|||
|
n.d.: not determined |
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|
van Bergen en Henegouwen Cell Communication and Signaling 2009 7:24 doi:10.1186/1478-811X-7-24 |
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