Short report
High Erk activity suppresses expression of the cell cycle inhibitor p27Kip1 in colorectal cancer cells
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* Corresponding author: Stephan M Feller stephan.feller@imm.ox.ac.uk
1 Cell Signalling Group, Department of Molecular Oncology, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford University, Headley Way, Oxford OX3 9DS, UK
2 Institut für Medizinische Strahlenkunde und Zellforschung, Universität Würzburg, Würzburg, Germany
3 Current address: Theodor Boveri Institut, Physiologische Chemie II, Biozentrum, Universität Würzburg, Würzburg, Germany
Cell Communication and Signaling 2010, 8:1 doi:10.1186/1478-811X-8-1
Published: 2 February 2010Additional files
Additional file 1:
Origin of CRC cell lines.
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Additional file 2:
Methods description.
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Additional file 3:
Expression levels of p27Kip1 in 10 CRC cell lines with high or low Erk activity.
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Additional file 4:
Effect of the MEK1/2 U0126 on the morphology of HCT 116 cells.
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