Editorial
Early beginnings - the emergence of complex signaling systems and cell-to-cell communication
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Correspondence: Stephan M Feller stephan.feller@imm.ox.ac.uk
Cell Signalling Group, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK
Cell Communication and Signaling 2010, 8:16 doi:10.1186/1478-811X-8-16
Published: 12 July 2010First paragraph (this article has no abstract)
The protein universe is currently still expanding [1] and so is the realm of cellular signaling proteins. Although in selected cases the genome size and number of genes in a species may substantially decrease as a reflection of a very narrow ecological niche and specialised lifestyle [2], overall there is an ever-increasing complexity in cellular signalling networks clearly evident throughout evolution.