Figure 2.

A. Summary of ELM output for β-dystroglycan cytoplasmic domain. Horizontal grey lines represent the primary sequence of the dystroglycan cytoplasmic domain, pink bars are low complexity and orange bars are disordered regions, blue and red boxes represent the position(s) of specific linear motifs as described on the left. Numbers represent the number of occurrences of each motif in the sequence, full annotation can be found at http://www.elm.eu.org webcite. B Scheme showing detail of sequence and position of interaction sites in the β-dystroglycan juxtamembrane region including Rapsyn, ERM, ERK and NLS. C Scheme showing detail of sequence and position of interaction sites in the β-dystroglycan carboxy terminus including WW SH3 and SH2. X denotes any residue within the ELM consensus, and pY represents phosphorylated tyrosine.