Model for PKCβII and RACK1 interaction. (A). In resting state, there is no interaction between RACK1 and inactive PKCβII. (B). Activation of PKCβII leads to the interaction between the active form of the kinase and RACK1. RACK1 then shuttles the active PKCβII to the site of its substrate.
Adams et al. Cell Communication and Signaling 2011 9:22 doi:10.1186/1478-811X-9-22