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1.

1316
Accesses

Review   Open Access Highly Accessed

Regulation of MicroRNA Biogenesis: A miRiad of mechanisms

Brandi N Davis, Akiko Hata Cell Communication and Signaling 2009, 7:18 (10 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

2.

1021
Accesses

Review   Open Access Highly Accessed

Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

Ralf Hass, Cornelia Kasper, Stefanie Böhm, Roland Jacobs Cell Communication and Signaling 2011, 9:12 (14 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

3.

1012
Accesses

Review   Open Access Highly Accessed

RACK1, A multifaceted scaffolding protein: Structure and function

David R Adams, Dorit Ron, Patrick A Kiely Cell Communication and Signaling 2011, 9:22 (6 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

4.

923
Accesses

Research   Open Access

Cell plasticity in wound healing: paracrine factors of M1/ M2 polarized macrophages influence the phenotypical state of dermal fibroblasts

Diana TA Ploeger, Nynke A Hosper, Martin Schipper, Jasper A Koerts, Saskia de Rond, Ruud A Bank Cell Communication and Signaling 2013, 11:29 (19 April 2013)

Abstract | Provisional PDF | PubMed

5.

875
Accesses

Review   Open Access Highly Accessed

Rac and Rho GTPases in cancer cell motility control

Matteo Parri, Paola Chiarugi Cell Communication and Signaling 2010, 8:23 (7 September 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

6.

835
Accesses

Research   Open Access

The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells

Hui Cai, Yan Xu Cell Communication and Signaling 2013, 11:31 (24 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

760
Accesses

Review   Open Access Highly Accessed

PARP-1 cleavage fragments: signatures of cell-death proteases in neurodegeneration

Ganta Chaitanya, Jonathan S Alexander, Phanithi Babu Cell Communication and Signaling 2010, 8:31 (22 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

683
Accesses

Review   Open Access Highly Accessed

Mesenchymal stem cells as all-round supporters in a normal and neoplastic microenvironment

Ralf Hass, Anna Otte Cell Communication and Signaling 2012, 10:26 (3 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

621
Accesses

Review   Open Access Highly Accessed

PDZ domains and their binding partners: structure, specificity, and modification

Ho-Jin Lee, Jie J Zheng Cell Communication and Signaling 2010, 8:8 (28 May 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

607
Accesses

Research   Open Access

The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction

Isabel Almudi, Ingrid Poernbacher, Ernst Hafen, Hugo Stocker Cell Communication and Signaling 2013, 11:26 (16 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

550
Accesses

Review   Open Access Highly Accessed

Calcium signaling around Mitochondria Associated Membranes (MAMs)

Simone Patergnani, Jan M Suski, Chiara Agnoletto, Angela Bononi, Massimo Bonora, Elena De Marchi, Carlotta Giorgi, Saverio Marchi, Sonia Missiroli, Federica Poletti, Alessandro Rimessi, Jerzy Duszynski, Mariusz R Wieckowski, Paolo Pinton Cell Communication and Signaling 2011, 9:19 (22 September 2011)

Abstract | Full text | PDF | PubMed

12.

539
Accesses

Review   Open Access

Light microscopy applications in systems biology: opportunities and challenges

Paul Michel Aloyse Antony, Christophe Trefois, Aleksandar Stojanovic, Aidos Sagatovich Baumuratov, Karol Kozak Cell Communication and Signaling 2013, 11:24 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

13.

529
Accesses

Research   Open Access Highly Accessed

Effects of hypoxic culture conditions on umbilical cord-derived human mesenchymal stem cells

Antonina Lavrentieva, Ingrida Majore, Cornelia Kasper, Ralf Hass Cell Communication and Signaling 2010, 8:18 (16 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

481
Accesses

Research   Open Access

Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells

Sebastian Halbach, Kristoffer TG Rigbolt, Franziska U Wöhrle, Britta Diedrich, Christine Gretzmeier, Tilman Brummer, Jörn Dengjel Cell Communication and Signaling 2013, 11:30 (22 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

15.

428
Accesses

Short report   Open Access Highly Accessed

Identification of subpopulations in mesenchymal stem cell-like cultures from human umbilical cord

Ingrida Majore, Pierre Moretti, Ralf Hass, Cornelia Kasper Cell Communication and Signaling 2009, 7:6 (20 March 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Self-renewing mesenchymal stem cell-like subpopulations have been isolated from human umbilical cord tissue using a counterflow centrifugal elutriation technique and present an alternative to bone-marrow-derived stem cells.

16.

412
Accesses

Short report   Open Access

Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34

Konstantinos Poalas, Emeline M Hatchi, Nelia Cordeiro, Sonia M Dubois, Héloïse M Leclair, Claire Leveau, Catherine Alexia, Julie Gavard, Aimé Vazquez, Nicolas Bidère Cell Communication and Signaling 2013, 11:25 (16 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

17.

406
Accesses

Review   Open Access Highly Accessed

Connexins: a myriad of functions extending beyond assembly of gap junction channels

Hashem A Dbouk, Rana M Mroue, Marwan E El-Sabban, Rabih S Talhouk Cell Communication and Signaling 2009, 7:4 (12 March 2009)

Abstract | Full text | PDF | PubMed

18.

392
Accesses

Research   Open Access

Impact of the p53 status of tumor cells on extrinsic and intrinsic apoptosis signaling

Franziska Wachter, Michaela Grunert, Cristina Blaj, David M Weinstock, Irmela Jeremias, Harald Ehrhardt Cell Communication and Signaling 2013, 11:27 (17 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

19.

383
Accesses

Review   Open Access Highly Accessed

Illuminating the life of GPCRs

Ilka Böhme, Annette G Beck-Sickinger Cell Communication and Signaling 2009, 7:16 (14 July 2009)

Abstract | Full text | PDF | PubMed

20.

378
Accesses

Research   Open Access

PAG/Cbp suppression reveals a contribution of CTLA-4 to setting the activation threshold in T cells

Michal Smida, Clemens Cammann, Slavyana Gurbiel, Nadja Kerstin, Holger Lingel, Sabine Lindquist, Luca Simeoni, Monika C Brunner-Weinzierl, Miloslav Suchanek, Burkhart Schraven, Jonathan A Lindquist Cell Communication and Signaling 2013, 11:28 (19 April 2013)

Abstract | Full text | PDF | PubMed

21.

377
Accesses

Review   Open Access Highly Accessed

Phosphorylation meets nuclear import: a review

Jonathan D Nardozzi, Kaylen Lott, Gino Cingolani Cell Communication and Signaling 2010, 8:32 (23 December 2010)

Abstract | Full text | PDF | PubMed

22.

359
Accesses

Review   Open Access

Targeting self-renewal pathways in myeloid malignancies

William A Sands, Mhairi Copland, Helen Wheadon Cell Communication and Signaling 2013, 11:33 (15 May 2013)

Abstract | Provisional PDF | PubMed

23.

346
Accesses

Review   Open Access

Crk and CrkL adaptor proteins: networks for physiological and pathological signaling

Raymond B Birge, Charalampos Kalodimos, Fuyuhiko Inagaki, Shinya Tanaka Cell Communication and Signaling 2009, 7:13 (10 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

24.

334
Accesses

Review   Open Access

Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads

Kerrie L Taylor, Nicola J Grant, Nicholas D Temperley, E Elizabeth Patton Cell Communication and Signaling 2010, 8:11 (12 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

25.

331
Accesses

Review   Open Access

Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?

Matthias Sieber, Ria Baumgrass Cell Communication and Signaling 2009, 7:25 (27 October 2009)

Abstract | Full text | PDF | PubMed

26.

325
Accesses

Review   Open Access Highly Accessed

Activin signaling as an emerging target for therapeutic interventions

Kunihiro Tsuchida, Masashi Nakatani, Keisuke Hitachi, Akiyoshi Uezumi, Yoshihide Sunada, Hiroshi Ageta, Kaoru Inokuchi Cell Communication and Signaling 2009, 7:15 (18 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

321
Accesses

Research   Open Access

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition

Logan A Walsh, Sashko Damjanovski Cell Communication and Signaling 2011, 9:10 (2 May 2011)

Abstract | Full text | PDF | PubMed

28.

311
Accesses

Review   Open Access

Nucleoplasmic calcium signaling and cell proliferation: calcium signaling in the nucleus

Rodrigo R Resende, Lidia M Andrade, Andre G Oliveira, Erika S Guimarães, Silvia Guatimosim, M Fatima Leite Cell Communication and Signaling 2013, 11:14 (21 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

29.

312
Accesses

Review   Open Access

Expression and function of the insulin receptor substrate proteins in cancer

Katerina Mardilovich, Shannon L Pankratz, Leslie M Shaw Cell Communication and Signaling 2009, 7:14 (17 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

30.

307
Accesses

Review   Open Access Highly Accessed

The receptor RAGE: Bridging inflammation and cancer

Astrid Riehl, Julia Németh, Peter Angel, Jochen Hess Cell Communication and Signaling 2009, 7:12 (8 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

307
Accesses

Methodology   Open Access

A novel MCF-10A line allowing conditional oncogene expression in 3D culture

Ricarda Herr, Franziska U Wöhrle, Christina Danke, Christian Berens, Tilman Brummer Cell Communication and Signaling 2011, 9:17 (13 July 2011)

Abstract | Full text | PDF | PubMed

32.

304
Accesses

Research   Open Access

Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity

Sylvia S Amaral, André G Oliveira, Pedro E Marques, Jayane L D Quintão, Daniele A Pires, Rodrigo R Resende, Bruna R Sousa, Juliana G Melgaço, Marcelo A Pinto, Remo C Russo, Ariane K C Gomes, Lidia M Andrade, Rafael F Zanin, Rafaela V S Pereira, Cristina Bonorino, Frederico M Soriani, Cristiano X Lima, Denise C Cara, Mauro M Teixeira, Maria F Leite, Gustavo B Menezes Cell Communication and Signaling 2013, 11:10 (5 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

33.

296
Accesses

Review   Open Access Highly Accessed

Phosphatases in the cellular response to DNA damage

Alyson K Freeman, Alvaro NA Monteiro Cell Communication and Signaling 2010, 8:27 (22 September 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

34.

292
Accesses

Review   Open Access Highly Accessed

Nuclear trafficking of secreted factors and cell-surface receptors: new pathways to regulate cell proliferation and differentiation, and involvement in cancers

Nathalie Planque Cell Communication and Signaling 2006, 4:7 (18 October 2006)

Abstract | Full text | PDF | PubMed

35.

293
Accesses

Review   Open Access Highly Accessed

Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori

Steffen Backert, Marguerite Clyne, Nicole Tegtmeyer Cell Communication and Signaling 2011, 9:28 (1 November 2011)

Abstract | Full text | PDF | PubMed

36.

284
Accesses

Research   Open Access Highly Accessed

SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome

Bernard A Liu, Brett W Engelmann, Karl Jablonowski, Katherine Higginbotham, Andrew B Stergachis, Piers D Nash Cell Communication and Signaling 2012, 10:27 (14 September 2012)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

The human genome contains 111 SH2 domain containing proteins, which bind to activated protein tyrosine kinases. This research maps the SH2 interactome consisting of over 500 interactions, most of which are novel. Six general classes of SH2 domain specificity were found, which demonstrates the evolutionary similarity between these domains.

37.

284
Accesses

Research   Open Access

Molecular immunologic correlates of spontaneous latency in a rabbit model of pulmonary tuberculosis

Selvakumar Subbian, Paul O’Brien, Nicole L Kushner, Guibin Yang, Liana Tsenova, Blas Peixoto, Nirmalya Bandyopadhyay, Joel S Bader, Petros C Karakousis, Dorothy Fallows, Gilla Kaplan Cell Communication and Signaling 2013, 11:16 (28 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

38.

286
Accesses

Review   Open Access

Complexity of dopamine metabolism

Johannes Meiser, Daniel Weindl, Karsten Hiller Cell Communication and Signaling 2013, 11:34 (17 May 2013)

Abstract | Provisional PDF | PubMed

39.

281
Accesses

Research   Open Access

Up-regulation of COX-2/PGE2 by endothelin-1 via MAPK-dependent NF-κB pathway in mouse brain microvascular endothelial cells

Chih-Chung Lin, Hsi-Lung Hsieh, Ruey-Horng Shih, Pei-Ling Chi, Shin-Ei Cheng, Chuen-Mao Yang Cell Communication and Signaling 2013, 11:8 (23 January 2013)

Abstract | Full text | PDF | ePUB | PubMed

40.

278
Accesses

Book review   Open Access

The next evolutionary synthesis: from Lamarck and Darwin to genomic variation and systems biology

Jonathan BL Bard Cell Communication and Signaling 2011, 9:30 (3 November 2011)

Abstract | Full text | PDF | PubMed

41.

276
Accesses

Review   Open Access

Oocyte activation and phospholipase C zeta (PLCζ): diagnostic and therapeutic implications for assisted reproductive technology

Walaa M Ramadan, Junaid Kashir, Celine Jones, Kevin Coward Cell Communication and Signaling 2012, 10:12 (16 May 2012)

Abstract | Full text | PDF | PubMed

42.

277
Accesses

Review   Open Access

Atypical IκB proteins – nuclear modulators of NF-κB signaling

Marc Schuster, Michaela Annemann, Carlos Plaza-Sirvent, Ingo Schmitz Cell Communication and Signaling 2013, 11:23 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

43.

275
Accesses

Review   Open Access

H. pylori exploits and manipulates innate and adaptive immune cell signaling pathways to establish persistent infection

Anne Müller, Mathias Oertli, Isabelle C Arnold Cell Communication and Signaling 2011, 9:25 (1 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

44.

274
Accesses

Review   Open Access

Functions of the Lyn tyrosine kinase in health and disease

Evan Ingley Cell Communication and Signaling 2012, 10:21 (17 July 2012)

Abstract | Full text | PDF | PubMed

45.

273
Accesses

Review   Open Access Highly Accessed

Cancer stem cells in solid tumors: elusive or illusive?

Yvonne Welte, James Adjaye, Hans R Lehrach, Christian RA Regenbrecht Cell Communication and Signaling 2010, 8:6 (11 May 2010)

Abstract | Full text | PDF | PubMed

46.

272
Accesses

Research   Open Access

Signal transduction in primary human T lymphocytes in altered gravity – results of the MASER-12 suborbital space flight mission

Svantje Tauber, Swantje Hauschild, Claudia Crescio, Christian Secchi, Katrin Paulsen, Antonella Pantaleo, Angela Saba, Isabell Buttron, Cora Sandra Thiel, Augusto Cogoli, Proto Pippia, Oliver Ullrich Cell Communication and Signaling 2013, 11:32 (7 May 2013)

Abstract | Full text | PDF | ePUB | PubMed | Cited on BioMed Central

47.

272
Accesses

Research   Open Access

ARTD10 substrate identification on protein microarrays: regulation of GSK3β by mono-ADP-ribosylation

Karla LH Feijs, Henning Kleine, Anne Braczynski, Alexandra H Forst, Nicolas Herzog, Patricia Verheugd, Ulrike Linzen, Elisabeth Kremmer, Bernhard Lüscher Cell Communication and Signaling 2013, 11:5 (19 January 2013)

Abstract | Full text | PDF | ePUB | PubMed

48.

271
Accesses

Review   Open Access Highly Accessed

Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation

Rodrigo R Resende, Avishek Adhikari Cell Communication and Signaling 2009, 7:20 (27 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

49.

267
Accesses

Review   Open Access

Interaction of tumor cells with the microenvironment

Hendrik Ungefroren, Susanne Sebens, Daniel Seidl, Hendrik Lehnert, Ralf Hass Cell Communication and Signaling 2011, 9:18 (13 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

50.

261
Accesses

Research   Open Access Highly Accessed

Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

Susanne A Wolf, Anika Bick-Sander, Klaus Fabel, Perla Leal-Galicia, Svantje Tauber, Gerardo Ramirez-Rodriguez, Anke Müller, Andre Melnik, Tim P Waltinger, Oliver Ullrich, Gerd Kempermann Cell Communication and Signaling 2010, 8:12 (17 June 2010)

Abstract | Full text | PDF | PubMed

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