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26.

321
Accesses

Review   Open Access Highly Accessed

Activin signaling as an emerging target for therapeutic interventions

Kunihiro Tsuchida, Masashi Nakatani, Keisuke Hitachi, Akiyoshi Uezumi, Yoshihide Sunada, Hiroshi Ageta, Kaoru Inokuchi Cell Communication and Signaling 2009, 7:15 (18 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

27.

319
Accesses

Methodology   Open Access

A novel MCF-10A line allowing conditional oncogene expression in 3D culture

Ricarda Herr, Franziska U Wöhrle, Christina Danke, Christian Berens, Tilman Brummer Cell Communication and Signaling 2011, 9:17 (13 July 2011)

Abstract | Full text | PDF | PubMed

28.

317
Accesses

Research   Open Access

IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition

Logan A Walsh, Sashko Damjanovski Cell Communication and Signaling 2011, 9:10 (2 May 2011)

Abstract | Full text | PDF | PubMed

29.

307
Accesses

Review   Open Access

Complexity of dopamine metabolism

Johannes Meiser, Daniel Weindl, Karsten Hiller Cell Communication and Signaling 2013, 11:34 (17 May 2013)

Abstract | Provisional PDF | PubMed

30.

307
Accesses

Review   Open Access Highly Accessed

Phosphatases in the cellular response to DNA damage

Alyson K Freeman, Alvaro NA Monteiro Cell Communication and Signaling 2010, 8:27 (22 September 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

306
Accesses

Review   Open Access

Expression and function of the insulin receptor substrate proteins in cancer

Katerina Mardilovich, Shannon L Pankratz, Leslie M Shaw Cell Communication and Signaling 2009, 7:14 (17 June 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

32.

305
Accesses

Review   Open Access Highly Accessed

The receptor RAGE: Bridging inflammation and cancer

Astrid Riehl, Julia Németh, Peter Angel, Jochen Hess Cell Communication and Signaling 2009, 7:12 (8 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

33.

304
Accesses

Review   Open Access

Nucleoplasmic calcium signaling and cell proliferation: calcium signaling in the nucleus

Rodrigo R Resende, Lidia M Andrade, Andre G Oliveira, Erika S Guimarães, Silvia Guatimosim, M Fatima Leite Cell Communication and Signaling 2013, 11:14 (21 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

34.

303
Accesses

Research   Open Access

Altered responsiveness to extracellular ATP enhances acetaminophen hepatotoxicity

Sylvia S Amaral, André G Oliveira, Pedro E Marques, Jayane L D Quintão, Daniele A Pires, Rodrigo R Resende, Bruna R Sousa, Juliana G Melgaço, Marcelo A Pinto, Remo C Russo, Ariane K C Gomes, Lidia M Andrade, Rafael F Zanin, Rafaela V S Pereira, Cristina Bonorino, Frederico M Soriani, Cristiano X Lima, Denise C Cara, Mauro M Teixeira, Maria F Leite, Gustavo B Menezes Cell Communication and Signaling 2013, 11:10 (5 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

35.

287
Accesses

Review   Open Access Highly Accessed

Nuclear trafficking of secreted factors and cell-surface receptors: new pathways to regulate cell proliferation and differentiation, and involvement in cancers

Nathalie Planque Cell Communication and Signaling 2006, 4:7 (18 October 2006)

Abstract | Full text | PDF | PubMed

36.

288
Accesses

Review   Open Access Highly Accessed

Molecular mechanisms of gastric epithelial cell adhesion and injection of CagA by Helicobacter pylori

Steffen Backert, Marguerite Clyne, Nicole Tegtmeyer Cell Communication and Signaling 2011, 9:28 (1 November 2011)

Abstract | Full text | PDF | PubMed

37.

280
Accesses

Research   Open Access

Signal transduction in primary human T lymphocytes in altered gravity – results of the MASER-12 suborbital space flight mission

Svantje Tauber, Swantje Hauschild, Claudia Crescio, Christian Secchi, Katrin Paulsen, Antonella Pantaleo, Angela Saba, Isabell Buttron, Cora Sandra Thiel, Augusto Cogoli, Proto Pippia, Oliver Ullrich Cell Communication and Signaling 2013, 11:32 (7 May 2013)

Abstract | Full text | PDF | ePUB | PubMed | Cited on BioMed Central

38.

280
Accesses

Review   Open Access

Functions of the Lyn tyrosine kinase in health and disease

Evan Ingley Cell Communication and Signaling 2012, 10:21 (17 July 2012)

Abstract | Full text | PDF | PubMed

39.

275
Accesses

Research   Open Access Highly Accessed

SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome

Bernard A Liu, Brett W Engelmann, Karl Jablonowski, Katherine Higginbotham, Andrew B Stergachis, Piers D Nash Cell Communication and Signaling 2012, 10:27 (14 September 2012)

Abstract | Full text | PDF | ePUB | PubMed |  Editor’s summary

The human genome contains 111 SH2 domain containing proteins, which bind to activated protein tyrosine kinases. This research maps the SH2 interactome consisting of over 500 interactions, most of which are novel. Six general classes of SH2 domain specificity were found, which demonstrates the evolutionary similarity between these domains.

40.

278
Accesses

Book review   Open Access

The next evolutionary synthesis: from Lamarck and Darwin to genomic variation and systems biology

Jonathan BL Bard Cell Communication and Signaling 2011, 9:30 (3 November 2011)

Abstract | Full text | PDF | PubMed

41.

278
Accesses

Review   Open Access Highly Accessed

Cancer stem cells in solid tumors: elusive or illusive?

Yvonne Welte, James Adjaye, Hans R Lehrach, Christian RA Regenbrecht Cell Communication and Signaling 2010, 8:6 (11 May 2010)

Abstract | Full text | PDF | PubMed

42.

275
Accesses

Research   Open Access

Molecular immunologic correlates of spontaneous latency in a rabbit model of pulmonary tuberculosis

Selvakumar Subbian, Paul O’Brien, Nicole L Kushner, Guibin Yang, Liana Tsenova, Blas Peixoto, Nirmalya Bandyopadhyay, Joel S Bader, Petros C Karakousis, Dorothy Fallows, Gilla Kaplan Cell Communication and Signaling 2013, 11:16 (28 February 2013)

Abstract | Full text | PDF | ePUB | PubMed

43.

274
Accesses

Review   Open Access

Oocyte activation and phospholipase C zeta (PLCζ): diagnostic and therapeutic implications for assisted reproductive technology

Walaa M Ramadan, Junaid Kashir, Celine Jones, Kevin Coward Cell Communication and Signaling 2012, 10:12 (16 May 2012)

Abstract | Full text | PDF | PubMed

44.

268
Accesses

Review   Open Access

H. pylori exploits and manipulates innate and adaptive immune cell signaling pathways to establish persistent infection

Anne Müller, Mathias Oertli, Isabelle C Arnold Cell Communication and Signaling 2011, 9:25 (1 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

45.

266
Accesses

Review   Open Access

Atypical IκB proteins – nuclear modulators of NF-κB signaling

Marc Schuster, Michaela Annemann, Carlos Plaza-Sirvent, Ingo Schmitz Cell Communication and Signaling 2013, 11:23 (11 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

46.

265
Accesses

Research   Open Access

Up-regulation of COX-2/PGE2 by endothelin-1 via MAPK-dependent NF-κB pathway in mouse brain microvascular endothelial cells

Chih-Chung Lin, Hsi-Lung Hsieh, Ruey-Horng Shih, Pei-Ling Chi, Shin-Ei Cheng, Chuen-Mao Yang Cell Communication and Signaling 2013, 11:8 (23 January 2013)

Abstract | Full text | PDF | ePUB | PubMed

47.

265
Accesses

Review   Open Access Highly Accessed

Cholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation

Rodrigo R Resende, Avishek Adhikari Cell Communication and Signaling 2009, 7:20 (27 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

261
Accesses

Research   Open Access

Insulin and insulin like growth factor II endocytosis and signaling via insulin receptor B

Jimena Giudice, Lucia Soledad Barcos, Francisco F Guaimas, Alberto Penas-Steinhardt, Luciana Giordano, Elizabeth A Jares-Erijman, Federico Coluccio Leskow Cell Communication and Signaling 2013, 11:18 (11 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

49.

261
Accesses

Research   Open Access Highly Accessed

Cannabinoid receptor CB1 mediates baseline and activity-induced survival of new neurons in adult hippocampal neurogenesis

Susanne A Wolf, Anika Bick-Sander, Klaus Fabel, Perla Leal-Galicia, Svantje Tauber, Gerardo Ramirez-Rodriguez, Anke Müller, Andre Melnik, Tim P Waltinger, Oliver Ullrich, Gerd Kempermann Cell Communication and Signaling 2010, 8:12 (17 June 2010)

Abstract | Full text | PDF | PubMed

50.

262
Accesses

Review   Open Access

Interaction of tumor cells with the microenvironment

Hendrik Ungefroren, Susanne Sebens, Daniel Seidl, Hendrik Lehnert, Ralf Hass Cell Communication and Signaling 2011, 9:18 (13 September 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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