New insight into CCN3 interactions--nuclear CCN3 : fact or fantasy?

Perbal B.

Cell Commun Signal. 2006 Aug 8;4:6.

PMID: 16895594 [PubMed]

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The expression of ccn3 (nov) RNA and protein in the rat central nervous system is developmentally regulated.

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Mol Pathol. 2001 Jun;54(3):184-91.

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Nuclear addressing provides a clue for the transforming activity of amino-truncated CCN3 proteins.

Planque N, Long Li C, Saule S, Bleau AM, Perbal B.

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CCN3: Doctor Jekyll and Mister Hyde.

Perbal B.

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Nephroblastoma overexpressed/cysteine-rich protein 61/connective tissue growth factor/nephroblastoma overexpressed gene-3 (NOV/CCN3), a selective adrenocortical cell proapoptotic factor, is down-regulated in childhood adrenocortical tumors.

Doghman M, Arhatte M, Thibout H, Rodrigues G, De Moura J, Grosso S, West AN, Laurent M, Mas JC, Bongain A, Zambetti GP, Figueiredo BC, Auberger P, Martinerie C, Lalli E.

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Domain-specific CCN3 antibodies as unique tools for structural and functional studies.

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CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1.

Fukunaga-Kalabis M, Martinez G, Liu ZJ, Kalabis J, Mrass P, Weninger W, Firth SM, Planque N, Perbal B, Herlyn M.

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NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells.

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The aminoterminal insulin-like growth factor (IGF) binding domain of IGF binding protein-3 cannot be functionally substituted by the structurally homologous domain of CCN3.

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